| Research Output | Chronic Diseases Initiative in Africa | Divisional Statistics | Contact Details | Unit Statistics | Research Fields and Staff

(Including the Chronic Diseases Initiative in Africa)

Head of Division: Professor N.S. Levitt

Divisional Profile

The Division provides an inpatient and outpatient clinical service and sub-speciality training in adult endocrinology and diabetes.  It has close clinical links with Paediatric Endocrinology and Diabetes and Reproductive Endocrinology. Dr Joel Dave was appointed to a UCT Department of Education Senior Lecturer/Senior Specialist post and continues to work as a senior specialist in the division.  We are currently a host training centre for Endocrinologists on the African Continent with Dr Adedayo Adegite from Nigeria as our current supernumerary senior registrar


The Division is involved in a wide range of research activities, interacts with a number of international and local collaborators and is a member of the recently established Chronic Disease Initiative in Africa. The primary areas are:

Metabolic consequences of antiretroviral therapy in HIV+ patients:  Cross-sectional and longitudinal studies examining the metabolic consequences of HAART are underway.  These are being funded by the World Diabetes Foundation and Department of Health.

Burden of disease: The contribution of diabetes and other chronic diseases to the overall burden of disease pattern in the South African context has been studied in collaboration with Dr Debbie Bradshaw, BOD Group, MRC. A cross sectional survey of diabetes and other cardiovascular risk factors in the Black African community in Cape Town is underway.

Obesity: In collaboration with the Department of Human Biology, a number of studies are in progress examining the mechanisms underlying the aetiology of obesity and the metabolic sequelae thereof in black and white African women.

Addison’s Disease: The pathogenesis of Addison’s disease is being investigated in collaboration with the Universities of Florida, USA and Uppsala, Sweden.  Additionally a genetic component is being undertaken with Prof. She, Augusta, USA.  The metabolic and cardiovascular consequences of hydrocortisone replacement are currently being investigated in relation to Addison’s disease.

Health Systems Research: As part of the CDIA an integrated package of care including that related to diabetes and other chronic diseases is being developed for testing in a pragmatic cluster randomised trial.

Smoking in pregnancy:The development and testing of interventions directed at reducing smoking rates during pregnancy.


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